The main aim of the journal is to publish original contributions of scientific work on the role of chirality in chemistry and biochemistry in respect to biological, chemical, materials, pharmacological, spectroscopic and physical properties.
Papers on the chemistry (physiochemical, preparative synthetic, and analytical), physics, pharmacology, clinical pharmacology, toxicology, and other biological aspects of chiral molecules will be published.
Among the topics to be covered are:
Asymmetric synthesis, including development and characterization of chiral catalysts and mechanistic aspects
Isolation and structural elucidation of natural products
Chiroptical spectroscopies (ECD, VCD, OR, ROA, CPL, …) covering experimental, instrumental, theoretical and computational aspects
Homochirality and Spontaneous symmetry breaking in Nature
Theoretical aspects of chirality phenomenon and optical activity
Preparative and analytic separation of chiral molecules, including enantioselective chromatography and related techniques, liquid-liquid extractions, stereoisomer crystallizations
Chiral Supramolecular chemistry and chirality on nanoscale
Pharmacokinetics of chiral drugs (absorption, distribution, protein binding, biotransformation, etc.)
Pharmacodynamics of chiral drugs (drug-receptor interactions, pharmacological and toxicological activity)
Clinical pharmacology of chiral drugs (therapeutic index and response, bioavailability, adverse drug reactions, drug-drug interactions)
Regulatory and legal aspects in the development, testing, and marketing of chiral compounds
Stereochemistry of pesticides and other xenobiotics
In addition to original research papers, the journal publishes brief reviews, short communications, tutorials, conference reports, and book reviews.